2prime-O-(Nprime-Methylanthraniloyl)guanosine-3prime,5prime-cyclic monophosphate sodium saltA substrate for phosphodiesterase studies

2′-O-(N′-Methylanthraniloyl)guanosine-3′,5′-cyclic monophosphate sodium salt (CAS 83707-15-7)

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Synonym: Mant-cGMP sodium salt
Application: A substrate for phosphodiesterase studies
CAS Number: 83707-15-7
Purity: ≥98%
Molecular Weight: 500.33
Molecular Formula: C18H18N6O8P•Na
* Refer to Certificate of Analysis for lot specific data (including water content).
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2'-O-(N'-Methylanthraniloyl)guanosine-3',5'-cyclic monophosphate sodium saltis a fluorescent, cell-permeable analog of cGMP and is suitable as a substrate for PDE (phosphodiesterase) studies. The quantum yield is 0.26 and 10 μmol is approximately 5.00 mg.


References

Brown, J.E., et al. 1996. Biochem. Biophys. Res. Commun. 224, 684. Hiratsuka, T. 1982. J. Biol. Chem. 257, 13354.

Appearance :
Lyophilized powder
Physical State :
Solid
Solubility :
Soluble in water (1 mg/ml), and methanol.
Storage :
Store at -20° C
Melting Point :
>240° C (dec.)
Refractive Index :
n20D ~1.84 (Predicted)
Fluoresence :
λex ~350 nm, λem ~441 nm in water
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
44755111
MDL Number :
MFCD00467285
SMILES :
CNC1=CC=CC=C1C(=O)OC2C3C(COP(=O)(O3)[O-])OC2N4C=NC5=C4NC(=NC5=O)N.[Na+]

Download SDS (MSDS)

Certificate of Analysis

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