2′-Deoxyguanosine 5′-monophosphate disodium salt hydrateCAS: 33430-61-4, MF: C10H12N5O7P•Na2, MW: 391.18

2′-Deoxyguanosine 5′-monophosphate disodium salt hydrate (CAS 33430-61-4)

2′-Deoxyguanosine 5′-monophosphate disodium salt hydrate | CAS 33430-61-4 is rated 5.0 out of 5 by 1.
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Synonym: 2′-Deoxy-5′-guanylic acid disodium salt; 5′-dGMP disodium salt
CAS Number: 33430-61-4
Molecular Weight: 391.18
Molecular Formula: C10H12N5O7P•Na2
* Refer to Certificate of Analysis for lot specific data (including water content).
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Appearance :
Powder or granules
Physical State :
Solid
Storage :
Store at 4° C
Melting Point :
>245° C (dec.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
118076
SMILES :
C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2NC(=NC3=O)N)COP(=O)([O-])[O-])O.O.[Na+].[Na+]

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Rated 5 out of 5 by from Grabmann Grabmann, G. et al. (PubMed 23620371) performed a systematic capillary electrophoresis study on the effect of the buffer composition on the reactivity of the anticancer drug cisplatin to the DNA model 2'-deoxyguanosine 5'-monophosphate (dGMP). Kinetic experiments performed with CZE-UV showed a high reactivity of dGMP to cisplatin in pure water ( (1/2) = 4.1 0.7 h) but a significantly slowed down in a solution containing a carbonate/phosphate buffer supplemented with NaCl, resulting in a half-life of dGMP of 25 3 h. -SCBT Publication Review
Date published: 2015-05-06
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