20-carboxy Arachidonic Acid

20-carboxy Arachidonic Acid (CAS 79551-84-1)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 116ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: 20-carboxy AA
Application: A PPARα and PPARγ activator
CAS Number: 79551-84-1
Molecular Weight: 334.45
Molecular Formula: C20H30O4
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

20-carboxy arachidonic acid (20-COOH-AA) inhibits ion transport in the kidneys, much like its parent compound 20-HETE. Studies have shown that 20-carboxy arachidonic acid produces vasorelaxation of porcine coronary microvessels constricted with endothelin. Additionally, 20-carboxy arachidonic acid binds to and activates the isolated ligand binding domains of peroxisome proliferator-activated receptor α (PPARα, Kd = 0.87 ± 0.12 µM) and PPARγ (Kd = 1.7 ± 0.5 µM).


References

1. Fang, Xiang., et al., 2007. 20-carboxy-arachidonic acid is a dual activator of peroxisome proliferator-activated receptors alpha and gamma. Prostaglandins & other lipid mediators. 82(1-4): 175-84. PMID: 17164145

Formulation :
A solution in ethanol
Physical State :
Liquid
Storage :
Store at -20° C
Boiling Point :
78° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Transport :
UN 1170, Class 3, Packing group II
PubChem CID :
6437827
SMILES :
C(CCC(=O)O)C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 86ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 33ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.