2-ThioUTP tetrasodium salt CAS: 35763-29-2
MF: C9H11N2Na4O14P3S
MW: 588.13
A potent and selective P2Y2 agonist.

2-ThioUTP tetrasodium salt (CAS 35763-29-2)

2-ThioUTP tetrasodium salt | CAS 35763-29-2 is rated 5.0 out of 5 by 1.
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Alternate Names: 2-Thiouridine 5'-triphosphate tetrasodium salt
Application: 2-ThioUTP tetrasodium salt is a potent and selective P2Y2 agonist
CAS Number: 35763-29-2
Purity: >98%
Molecular Weight: 588.13
Molecular Formula: C9H11N2Na4O14P3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

2-ThioUTP tetrasodium salt is a potent and selective P2Y2 agonist (EC50 values are 0.035, 0.35 and 1.5μM for hP2Y2, hP2Y4 and hP2Y6 receptors respectively).


References

1. El-Tayeb, A., et al. 2006. J. Med. Chem. 49: 7076-7087. PMID: 17125260
2. Ko, H., et al. 2008. Bioorg. Med. Chem. 16: 6319-6332. PMID: 18514530

Physical State :
Liquid
Solubility :
Soluble in water (supplied pre-dissolved at a concentration of 10 mM).
Storage :
Store at -20° C
IC50 :
hP2Y2 receptor: EC5050 = 35 nM; hP2Y4 receptor: EC5050 = 350 nM; hP2Y6 receptor: EC5050 = 1.5 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
54591573
MDL Number :
MFCD12828755
SMILES :
[Na]OP(=O)(OC[[email protected]]1O[[email protected]]([[email protected]](O)[[email protected]@H]1O)n1ccc(=O)[nH]c1=S)OP(=O)(O[Na])OP(=O)(O[Na])O[Na]

Download SDS (MSDS)

Certificate of Analysis

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2-ThioUTP tetrasodium salt (CAS 35763-29-2)  Product Citations

See how others have used 2-ThioUTP tetrasodium salt (CAS 35763-29-2). Click on the entry to view the PubMed entry .

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PMID: # 24631773  J. Mol. Cell. Cardiol. 146-56.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Degagn Degagn , E. et al. (PubMed 22553130) reported that activation of the P2Y2 receptor by 2-ThioUTP promotes intestinal microtubule stabilization and mucosal re-epithelization in experimental colitis. -SCBT Publication Review
Date published: 2015-02-05
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