2-PMDQ CAS: 139047-55-5
MF: C21H23N5O
MW: 361.45
A potent and selective antagonist of the α1-AR adrenoceptor.

2-PMDQ (CAS 139047-55-5)

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Alternate Names: 2-[(4-Phenylpiperazin-1-yl)methyl]-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one
Application: 2-PMDQ is a potent and selective antagonist of the α1-AR adrenoceptor
CAS Number: 139047-55-5
Molecular Weight: 361.45
Molecular Formula: C21H23N5O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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2-PMDQ is a potent and selective α1-adrenoceptor (α1-AR) antagonist that displays antihypertensive properties.


References

Chern et al (1993) Studies on quinazolines. 5. 2,3-Dihydroimidazo[1,2-c]quinazoline derivatives - a novel class of potent and selective alpha (1) adrenoceptor antagonists and antihypertensive agents. J.Med.Chem. 36 2196.

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble to 10 mM in DMSO and in Ethanol
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
C1CN(CCN1CC2CN3C(=N2)C4=CC=CC=C4NC3=O)C5=CC=CC=C5

Download SDS (MSDS)

Certificate of Analysis

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