2-PMDQ is a potent and selective α1-adrenoceptor (α1-AR) antagonist that displays antihypertensive properties.
Chern et al (1993) Studies on quinazolines. 5. 2,3-Dihydroimidazo[1,2-c]quinazoline derivatives - a novel class of potent and selective alpha (1) adrenoceptor antagonists and antihypertensive agents. J.Med.Chem. 36 2196.
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