2-phenyl-amino-N6-endo-norbornyladenine is a potent and selective Adenosine A3-R (A3 AR) antagonist exhibiting a Ki of 37 nM with 60 and 200-fold selectivity over A1 and A2A adenosine receptors, respectively.
Perreira, M., Jiang, J., Klutz, A.M., et al. "Reversine" and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists. J Med Chem 48 4910-4918 (2005). Chen, S., Zhang, Q., Wu, X., et al. Dedifferentiation of lineage-committed cells by a small molecule. J Am Chem Soc 126 410-411 (2004).
See how others have used 2-phenyl-amino-N6-endo-norbornyladenine. Click on the entry to view the PubMed entry .
PMID: # 27510152 Liu, C.|Skaldin, M.|Wu, C.|Lu, Y.|Zavialov, AV.| et al. 2016. Sci Rep. 6: 31370.
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