2-Methoxy-antimycin A3Induces apoptosis in cancer cells by inhibition of Bcl-xL and Bcl-2

2-Methoxy-antimycin A3

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Application: Induces apoptosis in cancer cells by inhibition of Bcl-xL and Bcl-2
Molecular Weight: 534.60
Molecular Formula: C27H38N2O9
* Refer to Certificate of Analysis for lot specific data (including water content).
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2-Methoxy-antimycin A3 induces apoptosis in cancer cells by inhibiting Bcl-xL and Bcl-2 which depolarizes the mitochrondrial membrane potential. Reduces tumor size without apparent cytotoxicity.

Physical State :
Solid
Solubility :
Soluble in DMSO (10 mM), and ethanol (10 mM).
Storage :
Store at -20° C
Boiling Point :
~750.2° C at 760 mmHg (Predicted)
Density :
~1.2 g/cm3 (Predicted)
Refractive Index :
n20D 1.54 (Predicted)
pK Values :
pKa: 12.1 (Predicted), pKb: 0.89 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
6610329
SMILES :
CCCC[C@@H]1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)OC)C)OC(=O)CC(C)C

Download SDS (MSDS)

Certificate of Analysis

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