2-Hydroxy Oleic AcidAn inducer of cell cycle arrest and apoptosis

2-Hydroxy Oleic Acid (CAS 56472-29-8)

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Synonym: 2-Hydroxyoleic Acid; Minerval; 2OHOA
Application: An inducer of cell cycle arrest and apoptosis
CAS Number: 56472-29-8
Molecular Weight: 298.46
Molecular Formula: C18H34O3
* Refer to Certificate of Analysis for lot specific data (including water content).
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2-Hydroxy Oleic Acid is an inducer of cell cycle arrest and apoptosis in several cancer cell lines, including glioma, leukemia, breast and colon cancer lines. 2-Hydroxy Oleic Acid increases sphingomyelin (SM) levels in the membranes of tumor cells, which typically display decreased SM membrane content, and remodeled membranes, compared with normal cells. The compound has no effect on SM levels in non-cancer cells.

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Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Hello, how is the 2 Hydroxyoleic Acid intake for Glioma, do we need to dissolve in Ethanol ? water or encapsulate the powder,

Asked by: Eti Lavi
Thank you for your question. This is soluble in DMSO: >20 mg/mL. It is also slightly soluble in chloroform and methanol. We have not tested in Glioma, however, I have included a link that may be helpful. https://www.ncbi.nlm.nih.gov/pubmed/23133576 If you have any further questions, please contact our European Technical Service team. You can reach them by phone at Toll Free: +49 6221 4503 0, by email at: europe@scbt.com or by live chat directly on our website, www.scbt.com
Answered by: Tech Service
Date published: 2017-07-06
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