2-AminoacridoneA highly fluorescent aromatic

2-Aminoacridone (CAS 27918-14-5)

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Synonym: 2-Amino-9(10H)-acridinone; 2-amino-10H-acridin-9-one; AMAC
Application: A highly fluorescent aromatic
CAS Number: 27918-14-5
Purity: ≥98%
Molecular Weight: 210.23
Molecular Formula: C13H10N2O
* Refer to Certificate of Analysis for lot specific data (including water content).
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2-Aminoacridone is a highly fluorescent aromatic, which contains a primary amine group that reacts with an aldehyde group at the reducing end of a carbohydrate. This compound can detect picomolar levels of glycan compounds. This compound is useful in the derivatization of glycans to allow for the analysis of complex oligosaccharides using micellar electrokinetic capillary chromatography and reverse- and normal-phase chromatography coupled with mass spectroscopy to determine relative concentrations and structural identity of individual oligosaccharides.


References

1. Jackson, P. 1994. Anal. Biochem. 216(2): 243-252. PMID: 8179179
2. Jackson, P. 1996. Mol. Biotechnol. 5(2): 101-123. PMID: 8734424
3. Harvey, D.J. 2000. J. Am. Soc. Mass Spectrom. 11(10): 900-915. PMID: 11014452
4. Tawada, A. et al. 2002. Glycobiology. 12(7): 421-426. PMID: 12122023

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in DMF, and DMSO.
Storage :
Store at room temperature
Fluoresence :
λex 420 nm, λem 538 nm in 0.1M Tris pH 8.0
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
121965
SMILES :
C1=CC=C2C(=C1)C(=O)C3=C(N2)C=CC(=C3)N

Download SDS (MSDS)

Certificate of Analysis

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