2-(4prime-(dimethylamino)phenyl)-6-methyl-benzothiazole CAS: 10205-62-6
MF: C16H16N2S
MW: 268.38
An uncharged derivative of Thioflavin-T.

2-(4′-(dimethylamino)phenyl)-6-methyl-benzothiazole (CAS 10205-62-6)

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Alternate Names: BTA-2
Application: 2-(4′-(dimethylamino)phenyl)-6-methyl-benzothiazole is an uncharged derivative of Thioflavin-T
CAS Number: 10205-62-6
Molecular Weight: 268.38
Molecular Formula: C16H16N2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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2-(4′-(dimethylamino)phenyl)-6-methyl-benzothiazole is an uncharged derivative of Thioflavin-T, displaying 6-fold higher affinity than Thioflavin-T, and shows high affinity for amyloid deposits [Ki = 143 nM for Ab(1-40)]. It can cross the blood brain barrier, and stains both plaques and neurofibrillary tangles in post mortem Alzheimer's disease brain.

Physical State :
Solid
Storage :
Desiccate at -20° C
Fluoresence :
λex 356 nm, λem 437 nm in DMSO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
CC1=CC2=C(C=C1)N=C(S2)C3=CC=C(C=C3)N(C)C

Download SDS (MSDS)

Certificate of Analysis

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