(1R,2R)-trans-1,2-Cyclohexanediol (CAS 1072-86-2)

(1R,2R)-trans-1,2-Cyclohexanediol (TCHD) serves as a significant intermediate in the synthesis of diverse organic compounds and finds wide-ranging applications in the chemical industry. Extensive scientific research has focused on exploring the potential of (1R,2R)-trans-1,2-Cyclohexanediol in biochemistry, pharmacology, and medicinal chemistry. In biochemistry, (1R,2R)-trans-1,2-Cyclohexanediol acts as a substrate for enzymes such as alcohol dehydrogenase and aldehyde dehydrogenase. Its pharmacological potential has been studied in relation to its anti-tumor, neuroprotective, and hepatoprotective properties. Furthermore, (1R,2R)-trans-1,2-Cyclohexanediol serves as a valuable building block in medicinal chemistry for synthesizing various pharmaceuticals, including anti-inflammatory agents and antifungal agents. While the exact mechanism of action of (1R,2R)-trans-1,2-Cyclohexanediol is not fully understood, it is believed to operate through multiple pathways. In biochemistry, enzymes like alcohol dehydrogenase and aldehyde dehydrogenase metabolize (1R,2R)-trans-1,2-Cyclohexanediol, leading to the formation of other compounds such as cyclohexanol and cyclohexanone. In pharmacology, (1R,2R)-trans-1,2-Cyclohexanediol has demonstrated inhibitory effects on cancer cell growth and exhibited neuroprotective properties against oxidative stress. Its applications in medicinal chemistry involve serving as a versatile building block for pharmaceutical synthesis, each with its distinct mechanism of action.