Molecular structure of 17α-Hydroxyprogesterone Caproate, CAS Number: 630-56-8
17α-Hydroxyprogesterone Caproate (CAS 630-56-8)
See product citations (5)
Alternate Names:
Hydroxyprogesterone hexanoate
CAS Number:
630-56-8
Purity:
≥98%
Molecular Weight:
428.60
Molecular Formula:
C27H40O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
17α-Hydroxyprogesterone Caproate is an artificial progestin compound derived from 17α-hydroxyprogesterone. Presenting as a white crystalline powder, it readily dissolves in ethanol and displays limited solubility in water. It serves as useful in scientific research, finding utility in laboratory applications. Although the exact workings of 17α-Hydroxyprogesterone Caproate remain partly elusive, it is believed to bind to progesterone receptors within cells, thereby influencing the expression of genes pivotal to cell cycle progression and apoptosis.
17α-Hydroxyprogesterone Caproate (CAS 630-56-8) References
- 17alpha-hydroxyprogesterone caproate for the prevention of preterm delivery: A cost-effectiveness analysis. | Odibo, AO., et al. 2006. Obstet Gynecol. 108: 492-9. PMID: 16946206
- 17α Hydroxyprogesterone caproate for prevention of recurrent spontaneous preterm birth. | Merlob, P., et al. 2012. Reprod Toxicol. 33: 15-9. PMID: 22120850
- Progesterone is not the same as 17α-hydroxyprogesterone caproate: implications for obstetrical practice. | Romero, R. and Stanczyk, FZ. 2013. Am J Obstet Gynecol. 208: 421-6. PMID: 23643669
- 17α-hydroxyprogesterone caproate access in the Louisiana Medicaid population. | Orsulak, MK., et al. 2015. Clin Ther. 37: 727-32. PMID: 25700945
- Population pharmacokinetics of 17α-hydroxyprogesterone caproate in singleton gestation. | Sharma, S., et al. 2016. Br J Clin Pharmacol. 82: 1084-93. PMID: 27133963
- Vaginal progesterone vs intramuscular 17α-hydroxyprogesterone caproate for prevention of recurrent spontaneous preterm birth in singleton gestations: systematic review and meta-analysis of randomized controlled trials. | Saccone, G., et al. 2017. Ultrasound Obstet Gynecol. 49: 315-321. PMID: 27546354
- Meta-analysis of randomized controlled trials comparing 17α-hydroxyprogesterone caproate and vaginal progesterone for the prevention of recurrent spontaneous preterm delivery. | Oler, E., et al. 2017. Int J Gynaecol Obstet. 138: 12-16. PMID: 28369874
- 17α-Hydroxyprogesterone Caproate and the Risk of Glucose Intolerance in Pregnancy: A Systematic Review and Meta-analysis. | Eke, AC., et al. 2019. Obstet Gynecol. 133: 468-475. PMID: 30741815
- 17-OHPC to Prevent Recurrent Preterm Birth in Singleton Gestations (PROLONG Study): A Multicenter, International, Randomized Double-Blind Trial. | Blackwell, SC., et al. 2020. Am J Perinatol. 37: 127-136. PMID: 31652479
- Accelerated Approval of 17α-Hydroxyprogesterone Caproate: A Cautionary Tale. | Godlewski, BJ., et al. 2020. Obstet Gynecol. 135: 1207-1213. PMID: 32282587
- In utero exposure to 17α-hydroxyprogesterone caproate and risk of cancer in offspring. | Murphy, CC., et al. 2022. Am J Obstet Gynecol. 226: 132.e1-132.e14. PMID: 34767803
- 17α-Hydroxyprogesterone Caproate Inhibits Cytokine Production via Suppression of NF-κB Activation. | Hu, T., et al. 2022. Front Pharmacol. 13: 831315. PMID: 35330839
- Vaginal progesterone compared with intramuscular 17-alpha-hydroxyprogesterone caproate for prevention of recurrent preterm birth in singleton gestations: a systematic review and meta-analysis. | Boelig, RC., et al. 2022. Am J Obstet Gynecol MFM. 4: 100658. PMID: 35562009
- Regional differences in utilization of 17α-hydroxyprogesterone caproate (17-OHP). | Hart, JM., et al. 2022. J Perinat Med. 50: 1203-1209. PMID: 35654442
- Immune effects of 17α-hydroxyprogesterone caproate. | Al-Lami, RA. 2022. Am J Obstet Gynecol. 227: 671-675. PMID: 35779586
Inhibitor of:
3β-HSD.Activator of:
Placental lactogen I.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
17α-Hydroxyprogesterone Caproate, 200 mg | sc-287311 | 200 mg | $128.00 |