17-GMB-APA-GAA useful analog of geldanamycin and Hsp90 inhibitor

17-GMB-APA-GA

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Synonym: 17-(3-(4-Maleimidobutyrcarboxamido)propylamino)-demethoxygeldanamycin
Application: A useful analog of geldanamycin and Hsp90 inhibitor
Molecular Weight: 767.87
Molecular Formula: C39H53N5O11
* Refer to Certificate of Analysis for lot specific data (including water content).
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17-GMB-APA-GA is an analog of geldanamycin containing a maleimido moiety suitable for preparation of geldanamycin immunoconjugates. 17-GMB-APA-GA is an Hsp90 inhibitor.


References

1: R. Mandler et al. Cancer Res. 2004 64 1460 2: R. Mandler et al. Bioconjug. Chem. 2002 13 786 3: R. Mandler et al. J. Natl. Cancer Inst. 2000 92 1573

Physical State :
Solid
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
57370016
SMILES :
CO[C@H]1C[C@H](C)CC2=C(NCCCNC(=O)CCCN3C(=O)C=CC3=O)C(=O)C=C(NC(=O)C(=CC=C[C@H](OC)[C@@H](OC(=O)N)C(=C[C@H](C)[C@H]1O)C)C)C2=O

Download SDS (MSDS)

Certificate of Analysis

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