13-cis Retinoic Acid-d5A labeled retinoid and teratagen used for severe acne treatment

13-cis Retinoic Acid-d5

13-cis Retinoic Acid-d5 is rated 5.0 out of 5 by 1.
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Synonym: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2Z,4E,6E,8E-nonatetranenoic Acid-d5; Isotretinoin-d5; 13-cis-Vitamin A Acid-d5; Accutane-d5; Isotretinoin-d5; Isotrex-d5; IsotrexGel-d5; Neovitamin A Acid-d5; Ro 4-3780-d5; Roaccutan-d5; Roaccutane-d5
Application: A labeled retinoid and teratagen used for severe acne treatment
Molecular Weight: 305.47
Molecular Formula: C20H23D5O2
* Refer to Certificate of Analysis for lot specific data (including water content).
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13-cis Retinoic Acid-d5 is used as a treatment for severe acne, and is presently being studied in conjuction with the treatment of photoaged skin.


References

Lerche, C., et al.: Exp. Dermatol., 17, 972 (2008) Sato, T., et al.: J. Med. Chem., 51, 7705 (2008) Gan, J., et al.: Chem. Res. Toxicol., 22, 690 (2009) Macejova, D., et al.: Toxicol. Lett., 184, 114 (2009) Chen, P., et al.: Toxicol. App. Pharmacol., 234, 143 (2009)

Appearance :
Yellow
Physical State :
Solid
Solubility :
Chloroform
Storage :
Store at -20° C
Melting Point :
158-160
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
54305565
SMILES :
[2H]C1(CCC(C(=C1C([2H])([2H])[2H])C=CC(=CC=CC(=CC(=O)O)C)C)(C)C)[2H]

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Various publications cite the use of the Various publications cite the use of the labeled retinoid 13-cis Retinoic Acid-d5 in the treatment of photoaged skin. -SCBT Publication Review
Date published: 2015-01-26
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