1-Naphthylacetyl Spermine is a poliamine amide. It is a potent Spermidine uptake inhibitor. 1-Naphthylacetyl Spermine acts as a selective antagonist of GluR (Ca2+-permeable AMPA receptors) and protects huppocampal neurons against global ischemia-induced cell death. AMPA is a transmembrane glutamate receptor composed of the subunits GluR-1,2,3,4.
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