Molecular structure of 1-Aminoanthracene, CAS Number: 610-49-1
1-Aminoanthracene (CAS 610-49-1)
Alternate Names:
1-anthrylamine
Application:
1-Aminoanthracene is a fluorophore used in fluorescence absorption assays
CAS Number:
610-49-1
Purity:
≥90%
Molecular Weight:
193.24
Molecular Formula:
C14H11N
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1-Aminoanthracene is a fluorophore, which functions as a polarity sensitive hydrophobic probe useful in the identification of protein cavities. Studies indicate that 1-Aminoanthracene can potentiate GABAergic transmission and bind to anesthetic site in horse spleen apoferritin (HSAF). These studies suggest that 1-Aminoanthracene is beneficial in tracking the distribution of anesthetics at the cellular and subcellular levels. This compound could also reversibly inhibit the mobility of Xenopus tadpoles. Furthermore the fluorescence ability of the compound makes it useful in imaging studies, displaying localization in neuronal tissues.
1-Aminoanthracene (CAS 610-49-1) References
- Microbial metabolism of 1-aminoanthracene by Beauveria bassiana. | Zhan, J. and Gunatilaka, AA. 2008. Bioorg Med Chem. 16: 5085-9. PMID: 18378148
- Identification of a fluorescent general anesthetic, 1-aminoanthracene. | Butts, CA., et al. 2009. Proc Natl Acad Sci U S A. 106: 6501-6. PMID: 19346473
- Effect of 1-aminoanthracene (1-AMA) binding on the structure of three lipocalin proteins, the dimeric β lactoglobulin, the dimeric odorant binding protein and the monomeric α1-acid glycoprotein. Fluorescence spectra and lifetimes studies. | Kmiecik, D. and Albani, JR. 2010. J Fluoresc. 20: 973-83. PMID: 20352304
- Direct modulation of microtubule stability contributes to anthracene general anesthesia. | Emerson, DJ., et al. 2013. J Am Chem Soc. 135: 5389-98. PMID: 23484901
- Investigation of the fluorescence quenching of 1-aminoanthracene by dissolved oxygen in cyclohexane. | Pagano, T., et al. 2014. J Phys Chem A. 118: 11512-20. PMID: 25427103
- Energy transfer studies between Trp residues of three lipocalin proteins family, α1-acid glycoprotein, (orosomucoid), β-lactoglobulin and porcine odorant binding protein and the fluorescent probe, 1-aminoanthracene (1-AMA). | Albani, JR., et al. 2015. J Fluoresc. 25: 167-72. PMID: 25597043
- Discovery of a novel general anesthetic chemotype using high-throughput screening. | McKinstry-Wu, AR., et al. 2015. Anesthesiology. 122: 325-33. PMID: 25603205
- 1-Aminoanthracene Transduction into Liposomes Driven by Odorant-Binding Protein Proximity. | Gonçalves, F., et al. 2018. ACS Appl Mater Interfaces. 10: 27531-27539. PMID: 30040883
- Two Engineered OBPs with opposite temperature-dependent affinities towards 1-aminoanthracene. | Gonçalves, F., et al. 2018. Sci Rep. 8: 14844. PMID: 30287882
- Substrate-Dependent Modulation of SIRT2 by a Fluorescent Probe, 1-Aminoanthracene. | Bi, D., et al. 2020. Biochemistry. 59: 3869-3878. PMID: 32941003
- 4-Ipomeanol and 2-aminoanthracene cytotoxicity in C3H/10T1/2 cells expressing rabbit cytochrome P450 4B1. | Smith, PB., et al. 1995. Biochem Pharmacol. 50: 1567-75. PMID: 7503758
- Determination of L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine in human plasma by high-performance liquid chromatography after pre-column derivatization with 1-aminoanthracene. | Longo, A., et al. 1996. J Chromatogr B Biomed Appl. 686: 129-39. PMID: 8971593
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Aminoanthracene, 1 g | sc-237465 | 1 g | $180.00 | |||
1-Aminoanthracene, 5 g | sc-237465A | 5 g | $410.00 |