Date published: 2025-11-15

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1-[3-(Trifluoromethyl)benzyl]piperazine (CAS 55513-16-1)

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CAS Number:
55513-16-1
Molecular Weight:
244.26
Molecular Formula:
C12H15F3N2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-[3-(Trifluoromethyl)benzyl]piperazine functions as a ligand for various receptors in experimental applications. It acts by binding to specific target sites, modulating the activity of these receptors. 1-[3-(Trifluoromethyl)benzyl]piperazine interact with certain neurotransmitter receptors, affecting the transmission of signals within the central nervous system. At the molecular level, 1-[3-(Trifluoromethyl)benzyl]piperazine may influence the conformation and function of these receptors, leading to altered cellular responses. Its mechanism of action involves the activation or inhibition of signaling pathways, ultimately impacting cellular processes. In experiment, 1-[3-(Trifluoromethyl)benzyl]piperazine is utilized to investigate the role of specific receptors and their involvement in various physiological and pathological conditions. Its interaction with target receptors provides insights into the molecular mechanisms underlying cellular signaling and communication.


1-[3-(Trifluoromethyl)benzyl]piperazine (CAS 55513-16-1) References

  1. The solid-phase synthesis and use of N-monosubstituted piperazines in chemical library synthesis.  |  Salvino, JM., et al. 2003. J Comb Chem. 5: 260-6. PMID: 12739942
  2. Discovery of novel dual functional agent as PPARgamma agonist and 11beta-HSD1 inhibitor for the treatment of diabetes.  |  Ye, YL., et al. 2009. Bioorg Med Chem. 17: 5722-32. PMID: 19574056
  3. Exploration of (S)-3-aminopyrrolidine as a potentially interesting scaffold for discovery of novel Abl and PI3K dual inhibitors.  |  Zhang, C., et al. 2011. Eur J Med Chem. 46: 1404-14. PMID: 21295380
  4. Discovery and biological evaluation of phthalazines as novel non-kinase TGFβ pathway inhibitors.  |  Kharbanda, A., et al. 2021. Eur J Med Chem. 223: 113660. PMID: 34246853

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-[3-(Trifluoromethyl)benzyl]piperazine, 1 g

sc-229749
1 g
$102.00

1-[3-(Trifluoromethyl)benzyl]piperazine, 5 g

sc-229749A
5 g
$394.00