1,2-O,O-Dioctadecyl-rac-glycero-3-phosphocholine (CAS 45322-29-0)

1,2-O,O-Dioctadecyl-rac-glycero-3-phosphocholine is a specialized synthetic phospholipid utilized predominantly in the field of biophysics to model and study the characteristics of lipid bilayers similar to those found in cell membranes. This molecule consists of a glycerol backbone with two attached octadecyl (stearyl) chains at the sn-1 and sn-2 positions, providing the lipid with a high degree of hydrophobicity and stability, which are essential for forming robust membrane structures. The inclusion of a phosphocholine group at the sn-3 position introduces a zwitterionic headgroup, which contributes both to the molecule′s water solubility and to its ability to interact effectively with other bilayer components. This structural design makes 1,2-O,O-Dioctadecyl-rac-glycero-3-phosphocholine an excellent tool for creating artificial membranes that closely mimic the natural properties of cellular membranes, enabling detailed studies on membrane dynamics, lipid-protein interactions, and the impact of lipid composition on membrane functionality. Researchers leverage this phospholipid to explore fundamental cellular processes such as signaling and transport, providing insights into the biophysical aspects of membrane behavior without any direct applications in medical or pharmaceutical contexts.