1,2-Dimyristoyl-rac-glycero-3-phosphocholine (CAS 18656-38-7)

1,2-Dimyristoyl-rac-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid that plays a crucial role in the study of membrane biophysics and nanotechnology. Comprised of two 14-carbon myristoyl chains linked to a racemic glycerol backbone and a phosphocholine headgroup, DMPC forms stable lipid bilayers and vesicles in aqueous solutions, closely mimicking the natural composition of cellular membranes. This amphipathic molecule is extensively used to investigate the physical properties of lipid layers, such as phase transitions, bilayer thickness, and fluidity, under various conditions. DMPC′s ability to transition between gel and liquid crystalline phases near physiological temperatures makes it particularly valuable for studying membrane dynamics and interactions with proteins and other biomolecules. Additionally, it serves as a model system for developing liposomal drug delivery technologies in nanotechnology, where its biocompatibility and behavior can be studied in controlled environments. By enabling detailed insights into lipid membrane structure and function, DMPC aids significant advancements in understanding cellular processes and developing new materials in both science and technology sectors without direct therapeutic applications.