1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-oneInhibits NO and PGE2 production and inhibits TXB2 production

1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one (CAS 18956-16-6)

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Application: Inhibits NO and PGE2 production and inhibits TXB2 production
CAS Number: 18956-16-6
Molecular Weight: 270.28
Molecular Formula: C16H14O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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This is the same as Cardamonin (sc-293984), except it possibly contains both the E and Z isomer, whereas Cardamonin is specifically the E isomer.

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM), and ethanol (25 mM).
Storage :
Store at room temperature
Melting Point :
177.58° C (Predicted)
Boiling Point :
~484.5° C at 760 mmHg (Predicted)
Density :
~1.3 g/cm3 (Predicted)
Refractive Index :
n20D 1.66 (Predicted)
IC50 :
KV1.3: IC50 = 2 nM (human); DLD-1: IC50 = 41.8 µM (human)
Ki Data :
Dengue virus type 2 NS3 protein: Ki= 377 µM (Dengue virus type 2 )
pK Values :
pKa: 7 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
641785
MDL Number :
MFCD00238554
SMILES :
COC1=CC(=CC(=C1C(=O)/C=C/C2=CC=CC=C2)O)O

Download SDS (MSDS)

Certificate of Analysis

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