1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose (PGG) induces apoptosis in DU145 and LNCaP cells. PGG effects downstream products of (FRAP) mTOR. PGG exhibits in vitro growth-inhibiting effect on human hepatocellular carcinoma cell line, SK-HEP-1 cells. 1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose is an inhibitor of PAI-1.
1. Oh, G.S., et al. 2001. Cancer Lett. 174: 17-24. PMID: 11675148
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KimKim, YH. et al. (PubMed 25737197) reported that 1,2,3,4,6-Penta-O-galloyl- -D-glucopyranose increases a population of T regulatory cells and inhibits IgE production in ovalbumin-sensitized mice. -SCBT Publication Review
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