USP9X/Y 항체(E-12)는 WB, IP, IF, IHC(P) and ELISA으로 USP9X of mouse, rat and human orgin, and USP9Y of human origin 를 감지하는 데에 추천한다 .
IP를 위해 agarose ;WB, IHC(P) and ELISA를 위해 HRP ;또는 IF, IHC(P) and FCM를 위해 phycoerythrin or FITC 에 결합된 Anti-USP9X/Y 항체 (E-12)를 제공한다.
WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for USP9X/Y Antibody (E-12) for WB and IHC(P) applications. These reagents are now offered in bundles with USP9X/Y Antibody (E-12) (see ordering information below).
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USP9X/Y Antibody (E-12) is a high quality monoclonal USP9X/Y antibody (also designated USP9X/USP9Y antibody) suitable for the detection of the USP9X/Y protein of mouse, rat and human origin. USP9X/Y Antibody (E-12) is available as both the non-conjugated anti-USP9X/Y antibody form, as well as multiple conjugated forms of anti-USP9X/Y antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP9X (ubiquitin specific peptidase 9, X-linked), also known as FAF or DFFRX, is a 2,547 amino acid member of the peptidase C19 family of ubiquitin proteases. Expressed ubiquitously in both fetal and adult tissue, USP9X is involved in the processing of ubiquitin precursors and ubiquitinated proteins, thereby preventing degradation and regulating protein turnover. USP9Y (ubiquitin specific peptidase 9, Y-linked), another member of the peptidase C19 family, is a 2,555 amino acid protein that is widely expressed and, like USPX, plays an important role in the processing of ubiquitin precursors and of ubiquitinated proteins. Defects in the gene encoding USP9X are implicated in Turner syndrome, a condition in which oocytes fail to proliferate and develop, while defects in the gene encoding USPPY are associated with non-obstructive azoospermia and infertility.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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