(S)-HexylHIBO CAS: 334887-48-8
MF: C12H20N2O4
MW: 256.3
A group I mGluR antagonist.

(S)-HexylHIBO (CAS 334887-48-8)

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Alternate Names: (S)-Hexylhomoibotenic acid
Application (S)-HexylHIBO is a group I mGluR antagonist
CAS 등록번호: 334887-48-8
분자량: 256.3
분자식: C12H20N2O4
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(S)-HexylHIBO is a group I mGluR antagonist and enantiomer of hexylHIBO (sc-203597). Metabotropic glutamate receptors (mGluR) are divided into three groups; group I, group II, and group III. Group I (mGluR-1 and mGluR-5) receptors are coupled to Gq/11 and are activators of phospholipase C. (S)-HexylHIBO is a group I mGluR antagonist which include metabotropic glutamate receptor subtypes mGluR-1 and mGluR-5.


References

1. Madsen, U., et al. 2001. J. Med. Chem. 44: 1051-1059.

Physical State :
Solid
용해도 :
Soluble to 20 mM in 1eq. NaOH
저장 :
Store at room temperature
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
PubChem CID :
SMILES :
CCCCCCC1=C(ONC1=O)C[[email protected]@H](C(=O)O)N

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