아미노 산1-130 mapping at the N-terminus of OCTN2 of human 의하고 기원한다
안티-OCTN1/2 항체 (H-9)는 WB, IP, IF and ELISA으로 mouse, rat and human유래의 OCTN1 and OCTN2 를 감지하는 데에 추천한다.
IP를 위해 agarose ;WB, IHC(P) and ELISA를 위해 HRP ;또는 IF, IHC(P) and FCM를 위해 phycoerythrin or FITC 에 결합된 Anti-OCTN1/2 항체 (H-9)를 제공한다.
WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for OCTN1/2 Antibody (H-9) for WB applications. This reagent is now offered in a bundle with OCTN1/2 Antibody (H-9) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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OCTN1/2 Antibody (H-9) is a high quality monoclonal OCTN1/2 antibody (also designated OCTN1/2 antibody) suitable for the detection of the OCTN1/2 protein of mouse, rat and human origin. OCTN1/2 Antibody (H-9) is available as both the non-conjugated anti-OCTN1/2 antibody form, as well as multiple conjugated forms of anti-OCTN1/2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Carnitine (b-hydroxy-g-trimethylaminobutyrate) is a small, highly polar compound that aids in the b-oxidation of long-chain fatty acids. Organic cation/carnitine transporters (OCTN) assist in the elimination of cationic compounds, including xenobiotics, and transport carnitine for reabsorption in the kidney. Similar to organic cation transporters (OCT), OCTN proteins localize to the plasma membrane of epithelial cells. OCTN1 is expressed in kidney, trachea, bone marrow and fetal liver. OCTN2 is abundantly expressed in kidney, skeletal muscle, placenta and heart. OCTN3 is strongly expressed in testis and weakly expressed in kidney. Mutations in the gene encoding OCTN2 leads to systemic carnitine deficiency (SCD), an autosomal recessive disorder characterized by cardiomyopathy, skeletal myopathy, lethargy, hypoglycemia and hyperammonemia.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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