human origin의 Mucin 16에서 C-terminus에 위치한 6419-6568 아미노산을 항원으로 사용하였습니다.
Mucin 16/MUC16 항체 (C-6)는 WB, IP, IF and ELISA으로 human유래의 Mucin 16 를 감지하는 데에 추천한다 .
IP를 위해 agarose ;WB, IHC(P) and ELISA를 위해 HRP ;또는 IF, IHC(P) and FCM를 위해 phycoerythrin or FITC 에 결합된 Anti-Mucin 16/MUC16 항체 (C-6)를 제공한다.
WB (RGB), IF, IHC(P) 와FCM, RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647결합제품도 있습니다.
WB (NIR), IF와FCM,Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems에 사용가능한 Alexa Fluor® 680 or Alexa Fluor® 790 결합제품도 있습니다.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Mucin 16/MUC16 Antibody (C-6) for WB applications. These reagents are now offered in bundles with Mucin 16/MUC16 Antibody (C-6) (see ordering information below).
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Mucin 16 Antibody (C-6) is a high quality monoclonal Mucin 16 antibody (also designated mucin 16, cell surface associated antibody or MUC16 antibody) suitable for the detection of the Mucin 16 protein of human origin. Mucin 16 Antibody (C-6) is available as both the non-conjugated anti-Mucin 16 antibody form, as well as multiple conjugated forms of anti-Mucin 16 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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