Levcromakalim CAS: 94535-50-9
MF: C16H18N2O3
MW: 286.33
An active enantiomer of the prototypical KATP(Kir6) channel opener cromakalim.

Levcromakalim (CAS 94535-50-9)

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Alternate Names: BRL 38227
Application Levcromakalim is an active enantiomer of the prototypical KATP(Kir6) channel opener cromakalim
CAS 등록번호: 94535-50-9
분자량: 286.33
분자식: C16H18N2O3
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* 참조분석증명서대량의 측정 데이터(함수량포함).
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Levcromakalim is an active enantiomer of the prototypical Kir6 (KATP) channel opener cromakalim.

Physical State :
Solid
용해도 :
Soluble in DMSO (10 mM).
저장 :
Store at room temperature
녹는점 :
194.54° C (Predicted)
비등점 :
482.34° C at 760 mmHg (Predicted)
밀도 :
1.31 g/cm3 (Predicted)
굴절률 :
n20D 1.62 (Predicted)
Optical Activity :
α20/D -66°, c = 1 in chloroform
IC50 :
Rattus norvegicus: IC50 = 40.1 nM; Cavia porcellus: IC50 = 300 nM; Sus scrofa: IC50 = 360 nM; Guinea pig trachea: IC50 = 490 nM
Ki 데이타 :
Sulfonylurea receptor 2, Kir6.2: Ki= 1.1 µM (human)
pK Values :
pKa: 13.18 (Predicted)
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
WGK Germany :
3
RTECS :
DJ2177500
PubChem CID :
MDL Number :
MFCD00864806
Beilstein Registry :
3622889
SMILES :
CC1([[email protected]]([[email protected]@H](C2=C(O1)C=CC(=C2)C#N)N3CCCC3=O)O)C

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Levcromakalim (CAS 94535-50-9)  논문정보

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인용 1 to 1 of 1 합계

PMID: # 28163191  Kitaguchi, T. et al. J Pharmacol Toxicol Methods. 85: 73-81.

인용 1 to 1 of 1 합계
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