cyclin E 항체(B-7) 는 마우스 monoclonal IgG2aκ, 10간행물에 인용, 이며 200 µg/ml으로 제공합니다.
human origin의 cyclin E에서 내부에 위치한 1-145 아미노산을 항원으로 사용하였습니다.
WB, IP, IF 와IHC(P)으로 human origin의 cyclin E을 검출할것을 권장합니다.
See cyclin E (E-4): sc-377100 for additional antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for cyclin E Antibody (B-7) for WB and IHC(P) applications. These reagents are now offered in bundles with cyclin E Antibody (B-7) (see ordering information below).
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Cyclins were first identified in invertebrates as proteins that oscillate dramatically through the cell cycle. These proteins have been well conserved through evolution and play a critical role in regulation of cell division. cyclin E, along with the three cyclin D proteins and cyclin C, has been shown to represent a putative G1 cyclin on the basis of its cyclic pattern of mRNA expression, with maximal levels being detected near the G1/S boundary. cyclin E has been found to be associated with the transcription factor E2F in a temporally regulated manner. The cyclin E/E2F complex is detected primarily during the G1 phase of the cell cycle and decreases as cells enter S phase. E2F is known to be a critical transcription factor for expression of several S phase specific proteins.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.