CKI-7 dihydrochloride CAS: 1177141-67-1
MF: C11H12ClN3O2S•2HCl
MW: 358.67
An inhibitor of CK1, SGK, S6K1 and MSK1.

CKI-7 dihydrochloride (CAS 1177141-67-1)

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Alternate Names: N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride
Application CKI-7 dihydrochloride is an inhibitor of CK1, SGK, p70 S6 Kinase (S6K1) and MSK1.
CAS 등록번호: 1177141-67-1
순도: ≥98%
분자량: 358.67
분자식: C11H12ClN3O2S•2HCl
추가 정보: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
* Refer to Certificate of Analysis for lot specific data (including water content).

CKI-7 dihydrochloride is a CK1 inhibitor which also inhibits SGK, S6K1 and MSK1. It inhibits SGK as potently as CK1.


References

Rena, G., et al. , D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a. EMBO J. Rep. 5, 60-65, (2004)

Physical State :
Solid
용해도 :
Soluble in water: >5 mg/mL
저장 :
Desiccate at -20° C
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
WGK Germany :
3
Transport :
UN 2811, Class 6.1, Packing group III
PubChem CID :
SMILES :
C1=CC(=C2C=CN=CC2=C1S(=O)(=O)NCCN)Cl.Cl.Cl

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