CB 1954 CAS: 21919-05-1
MF: C9H8N4O5
MW: 252.18
CB 1954 is a compound for gene therapy resrearch.

CB 1954 (CAS 21919-05-1)

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Alternate Names: 5-(1-Aziridinyl)-2,4-dinitrobenzamide
Application CB 1954 is a compound for gene therapy resrearch
CAS 등록번호: 21919-05-1
순도: >97%
분자량: 252.18
분자식: C9H8N4O5
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
* Refer to Certificate of Analysis for lot specific data (including water content).
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CB 1954 is a prodrug used in gene therapy research and activated by NAD(P)H quinone oxidoreductase.


References

Knox, R.J., et al., Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2: a novel co-substrate-mediated antitumor prodrug therapy. Cancer Res. 60, 4179, (2000)

Appearance :
Powder
Physical State :
Solid
저장 :
Store at -20° C
녹는점 :
189° C
비등점 :
427.2±45.0° C at 760 mmHg
밀도 :
1.7±0.1 g/cm3 (Predicted)
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
PubChem CID :
SMILES :
C1CN1C2=C(C=C(C(=C2)C(=O)N)[N+](=O)[O-])[N+](=O)[O-]

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CB 1954 (CAS 21919-05-1)  논문정보

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인용 1 to 1 of 1 합계

PMID: # 27099829  Müller, J. et al. 2015. Int J Parasitol Drugs Drug Resist. 5: 37-43.

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