Ac-YVAD-pNA CAS: 149231-66-3
MF: C29H36N6O10
MW: 628.63
A substrate for caspase-1 and caspase-4; cleavage is monitored colorimetrically at 405nm.

Ac-YVAD-pNA (CAS 149231-66-3)

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Alternate Names: Caspase-1 Substrate IV, Colorimetric
Application Ac-YVAD-pNA is a substrate for caspase-1 and caspase-4; cleavage is monitored colorimetrically at 405nm
CAS 등록번호: 149231-66-3
순도: ≥97%
분자량: 628.63
분자식: C29H36N6O10
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ac-YVAD-pNA is a substrate for caspase-1 and caspase-4. The sequence is a modification of pro-interleukin-1β Asp-116 cleavage site for caspase-1. It is similar to Ac-YVAD-AMC but cleavage is monitored colorimetrically at 405nm.


References

1. Thornberry, N.A., et al. 1992. Nature. 356: 768-774. PMID: 1574116
2. Reiter, L.A. 1994. Int. J. Pept. Protein Res. 43: 87-86. PMID: 8138355
3. Thornberry, N.A. 1994. Meth. Enzymol. 244: 615-63. PMID: 7845238

Appearance :
Powder
Physical State :
Solid
시퀀스 :
Ac-Tyr-Val-Ala-Asp-pNA (pNA=p-Nitroaniline)
용해도 :
Soluble in DMSO (10 mM), and water (partly miscible).Dilute with buffer (pH 7.5).
저장 :
Store at -20° C
비등점 :
~1108.93° C at 760 mmHg (Predicted)
밀도 :
~1.4 g/cm3 (Predicted)
굴절률 :
n20D 1.61 (Predicted)
연구용으로만 사용가능합니다. 진단이나 치료용으로 사용불가합니다.
PubChem CID :
MDL Number :
MFCD00274387
SMILES :
C[[email protected]@H](C(=O)N[[email protected]@H](CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)[[email protected]](C(C)C)NC(=O)[[email protected]](CC2=CC=C(C=C2)O)NC(=O)C

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Ac-YVAD-pNA (CAS 149231-66-3)  논문정보

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PMID: # 32332700  Cell Death Dis. 11: 277.

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