Safinamide mesylate CAS: 202825-46-5
MF: C17H19FN2O2•CH4O3S
MW: 398.45
A potent and selective MAO-B inhibitor.

Safinamide mesylate (CAS 202825-46-5)

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別名: (S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide; (S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]
アプリケーション: Safinamide mesylate is a potent and selective MAO-B inhibitor
CAS 番号: 202825-46-5
Purity: ≥98%
Molecular Weight: 398.45
Molecular Formula: C17H19FN2O2•CH4O3S
補足情報: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
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* Refer to Certificate of Analysis for lot specific data (including water content).
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Safinamide is a dopamine reuptake inhibitor by being a highly selective inhibitor of MAO-B (IC50 = 98 nM. Additionally, this compound has a high affinity for Na+ channels (IC50 = 8 μM.


参考文献

PMID: 20707760 PMID: 9580576

Appearance :
white to tan powder
Physical State :
Solid
Solubility :
Soluble in water (≥ 15 mg/ml).
保存方法 :
Store at 4° C
Optical Activity :
α20D +11.75°±2.25°, c = 1 in 95% acetic acid
IC50 :
MAO-B: IC50 = 98 nM; Na+ channels: IC50 = 8 µM
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
WGK Germany :
3
Transport :
UN 2811, Class 6.1, Packing group III
PubChem CID :
MDL Number :
MFCD15145475
SMILES :
C[[email protected]](C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F.CS(=O)(=O)O

Download SDS (MSDS)

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