(R)-5-Hydroxymethyl Tolterodine is a metabolite of Tolterodine, a potent and selective muscarinic receptor antagonist (mAChR M). In vitro, this compound prevented charbachol-induced contraction of isolated guinea pig bladder strips in a competitive and concentration-dependent manner. (R)-5-Hydroxymethyl Tolterodine is not selective for any muscrarinic receptor type but is selective for mAChR M over AChR.
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