(R)-5-Hydroxymethyl Tolterodine CAS: 207679-81-0
MF: C22H31NO2
MW: 341.49
A potent and selective antimuscarinic agent.

(R)-5-Hydroxymethyl Tolterodine (CAS 207679-81-0)

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別名: 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol; (+)-N,N-Diisopropyl-3-(2-hydroxy-5-hydroxymethylphenyl)-3-phenylpropylamine; PNU 200577
アプリケーション: (R)-5-Hydroxymethyl Tolterodine is a potent and selective antimuscarinic agent
CAS 番号: 207679-81-0
Molecular Weight: 341.49
Molecular Formula: C22H31NO2
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* Refer to Certificate of Analysis for lot specific data (including water content).
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(R)-5-Hydroxymethyl Tolterodine is a metabolite of Tolterodine, a potent and selective muscarinic receptor antagonist (mAChR M). In vitro, this compound prevented charbachol-induced contraction of isolated guinea pig bladder strips in a competitive and concentration-dependent manner. (R)-5-Hydroxymethyl Tolterodine is not selective for any muscrarinic receptor type but is selective for mAChR M over AChR.


参考文献

Palmer, L., et al.: J. Pharm. Biomed. Anal., 16, 155 (1997), Hills, C., et al.: Drugs, 55, 813 (1998), Wefer, J., et al.: World J. Urol., 19, 312 (2001),

Physical State :
Solid
保存方法 :
Store at -20° C
Melting Point :
68-72° C
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
PubChem CID :
SMILES :
CC(C)N(CC[[email protected]](C1=CC=CC=C1)C2=C(C=CC(=C2)CO)O)C(C)C

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