BTCP maleate CAS: 112726-66-6
MF: C19H25NS C4H4O4
MW: 415.6
A PCP analog and DAT inhibitor.

BTCP maleate (CAS 112726-66-6)

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アプリケーション: BTCP maleate is a PCP analog and DAT inhibitor
CAS 番号: 112726-66-6
Purity: ≥98%
Molecular Weight: 415.6
Molecular Formula: C19H25NS C4H4O4
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* Refer to Certificate of Analysis for lot specific data (including water content).
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BTCP maleate, a compound that differs from phencyclidine by containing a benzothiophenyl group instead of a phenyl ring, is a potent DAT (dopamine transporter) inhibitor. BTCP maleate competitively inhibits the binding of PCP to PCP receptors in the rat cerebellum. Studies suggest that this agent also protects dopaminergic neurons against neurotoxins.


参考文献

1. Vignon, J., et al. 1988. Eur. J. Pharmacol. 148: 427-436. PMID: 3384005
2. Maurice, T., et al. 1991. J. Neurochem. 56: 553-559. PMID: 1671086
3. Froimowitz, M., et al. 2000. J. Comput. Aided Mol. Des. 14: 135-146. PMID: 10721502
4. Martin-Fardon, R., et al. 2002. Pharmacol. Biochem. Behav. 72: 343-353. PMID: 11900805

Physical State :
Solid
Solubility :
Soluble in 100% ethanol, and DMSO (100 mM).
保存方法 :
Store at room temperature
Boiling Point :
425.4° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.62
試験・研究用以外には使用しないでください。 臨床及び体外診断には使用できません。
WGK Germany :
3
RTECS :
TM4571428
PubChem CID :
MDL Number :
MFCD00673901
SMILES :
OC(=O)/C=C\\C(=O)O.C1CCN(CC1)C1(CCCCC1)c1sc2ccccc2c1

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