Anti-UBE2D Antibody C-6 è un monoclonale di topo IgG1 κ UBE2D antibody, citato in 3 pubblicazioni, fornito in 200 µg/ml
specifico per un epitopo mappato tra gli amminoacidi 111-143 al C-terminus di UBE2D di origine human
UBE2D Antibody (C-6) é raccomandato per il rilevamento di reactive with all isoforms of UBE2D di origine mouse, rat, human e in WB, IP, IF and ELISA; anche reattivo con ulteriori specie, incluse e canine, bovine, porcine and avian
UBE2D Antibody (C-6) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Contattaci per ricevere un FREE 10 µg sample di UBE2D (C-6): sc-166278.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for UBE2D Antibody (C-6) for WB applications. These reagents are now offered in bundles with UBE2D Antibody (C-6) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
UBE2D Antibody (C-6) is a high quality monoclonal UBE2D antibody (also designated UBE2D antibody) suitable for the detection of the UBE2D protein of mouse, rat and human origin. UBE2D Antibody (C-6) is available as both the non-conjugated anti-UBE2D antibody form, as well as multiple conjugated forms of anti-UBE2D antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign, and improperly folded proteins by targeting them for proteosome degradation. UBE2D proteins, including UBE2D1 (ubiquitin-conjugating enzyme E2D1 or UBC5A), UBE2D2 (ubiquitin-conjugating enzyme E2D2 or UBC5B) and UBE2D3 (ubiquitin-conjugating enzyme E2D3 or UBC5C), are E2 ubiquitin-conjugating enzymes that catalyze the ubiquitination of IκBα in a phosphorylation and SCFB-TRCP-dependent manner. Specifically, E1 first transfers a ubiquitin residue to the E2 component (a UBE2D protein), and the UBE2D protein then associates with an E3 ubiquitin-protein ligase, which immediately transfers that residue to a protein that is targeted for degradation. In this fashion, the ubiquitin targets the IκBα for degradation by a proteasome thus lifting the inhibitory effect of IκBα on NFκB and allowing NFκB to enter the nucleus.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences