TudorSN Antibody (E-11): sc-166518

TudorSN Antibody (E-11) is a mouse monoclonal IgG1 antibody that detects TudorSN in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TudorSN plays a crucial role in the regulation of transcription, particularly in the Pim-1 regulation of Myb activity, and acts as a transcriptional activator of EBNA-2. TudorSN is primarily located in the nucleus, where TudorSN is essential for the assembly of the Stat6 transcriptome, facilitating the interaction between Stat6 and the co-activator CBP, which is vital for IL-4-dependent transcription. TudorSN interaction with specific proteins, including EAV, NSP1, GTF2E1, and GTF2E2, highlights TudorSN importance in various cellular processes and signaling pathways. Additionally, TudorSN contains staphylococcal nuclease-like domains that directly interact with amino acids 1099-1758 of CBP, further emphasizing TudorSN role in transcriptional regulation. TudorSN ability to form a ternary complex with Stat6 and POLR2A underscores TudorSN significance in gene expression modulation, making TudorSN a valuable target for research in cellular signaling and transcriptional control.

The preferred TudorSN antibody is TudorSN Antibody (F-5): sc-166676.