Date published: 2026-4-24

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Trichloroethylene (CAS 79-01-6)

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Application:
Trichloroethylene is a chlorinated ethylene solvent
CAS Number:
79-01-6
Purity:
≥98%
Molecular Weight:
131.39
Molecular Formula:
C2HCl3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Trichloroethylene, commonly abbreviated as TCE, is a chlorinated hydrocarbon with the chemical formula C2HCl3. This non-flammable, colorless liquid possesses a sweet smell and is primarily known for its extensive use as a solvent in industrial applications. TCE′s chemical structure, featuring three chlorine atoms attached to a double-bonded carbon skeleton, confers a high degree of volatility and an ability to dissolve a wide array of organic materials, which has historically made it a solvent of choice in degreasing operations for metal parts. Beyond its industrial uses, trichloroethylene has played a significant role in scientific research, particularly in the study of organic synthesis and materials science. In research environments, TCE is often used as a solvent to extract, purify, and recrystallize organic compounds due to its effectiveness in dissolving non-polar substances without altering or damaging sensitive chemical structures. Moreover, its properties have been exploited in the study of solvent effects on reaction mechanisms, helping chemists understand how changes in solvent polarity and reactivity influence the outcomes of chemical reactions. Trichloroethylene has also been a subject of environmental science research due to its persistence and impact on ecosystems, leading to studies focused on its degradation, environmental fate, and the development of remediation technologies to address TCE contamination in soils and groundwater.


Trichloroethylene (CAS 79-01-6) References

  1. Renal tubular cell necroptosis: A novel mechanism of kidney damage in trichloroethylene hypersensitivity syndrome mice.  |  Wang, Y., et al. 2021. J Immunotoxicol. 18: 173-182. PMID: 34788186
  2. Trichloroethylene modifies energy metabolites in the amniotic fluid of Wistar rats.  |  Su, AL., et al. 2022. Reprod Toxicol. 109: 80-92. PMID: 35301063
  3. Occupational trichloroethylene exposure and antinuclear antibodies: a cross-sectional study in China.  |  Purdue, M., et al. 2022. Occup Environ Med. 79: 717-720. PMID: 35504721
  4. Trichloroethylene remediation using zero-valent iron with kaolin clay, activated carbon and bacteria.  |  Zhu, J., et al. 2022. Water Res. 226: 119186. PMID: 36244142
  5. Recent advances and trends of trichloroethylene biodegradation: A critical review.  |  Wu, Z., et al. 2022. Front Microbiol. 13: 1053169. PMID: 36620007
  6. [Overview of occupational diseases induced by trichloroethylene and associated basic research].  |  Nasu Nakajima, T., et al. 2023. Sangyo Eiseigaku Zasshi. 65: 171-182. PMID: 37211415
  7. HMGB 1 acetylation mediates trichloroethylene-induced immune kidney injury by facilitating endothelial cell-podocyte communication.  |  Zhang, X., et al. 2023. Ecotoxicol Environ Saf. 259: 115042. PMID: 37216866
  8. Low-dose inhalation exposure to trichloroethylene induces dopaminergic neurodegeneration in rodents.  |  Adamson, A., et al. 2023. Toxicol Sci. 196: 218-228. PMID: 37669148
  9. Controlled-Release Materials for Remediation of Trichloroethylene Contamination in Groundwater.  |  Zhao, S., et al. 2023. Materials (Basel). 16: PMID: 37959642
  10. Parkinson's Disease Is Predominantly an Environmental Disease.  |  Dorsey, ER. and Bloem, BR. 2024. J Parkinsons Dis. 14: 451-465. PMID: 38217613

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Trichloroethylene, 500 ml

sc-251310
500 ml
$66.00

Trichloroethylene, 1 L

sc-251310A
1 L
$110.00