Molecular structure of Thiosildenafil, CAS Number: 479073-79-5
Thiosildenafil (CAS 479073-79-5)
See product citations (2)
Alternate Names:
5-[2-Ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidine-7-thione; 1-[[3-(4,7-Dihydro-1-methyl-3-propyl-7-thioxo- 1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine
Application:
Thiosildenafil is a PDE5A inhibitor
CAS Number:
479073-79-5
Purity:
98%
Molecular Weight:
490.64
Molecular Formula:
C22H30N6O3S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Thiosildenafil is an analog of Sildenafil and a novel pyrazolopyrimidinethiones as PDE5 inhibitor.
Thiosildenafil (CAS 479073-79-5) References
- Structure elucidation of sildenafil analogues in herbal products. | Blok-Tip, L., et al. 2004. Food Addit Contam. 21: 737-48. PMID: 15370823
- Rapid and reliable determination of illegal adulterant in herbal medicines and dietary supplements by LC/MS/MS. | Liang, Q., et al. 2006. J Pharm Biomed Anal. 40: 305-11. PMID: 16174560
- Isolation and identification of thiohomosildenafil and thiosildenafil in health supplements. | Zou, P., et al. 2008. J Pharm Biomed Anal. 47: 279-84. PMID: 18316170
- Structure elucidation of thioketone analogues of sildenafil detected as adulterants in herbal aphrodisiacs. | Reepmeyer, JC. and d'Avignon, DA. 2009. J Pharm Biomed Anal. 49: 145-50. PMID: 19042103
- Identification of a novel sildenafil analogue in an adulterated herbal supplement. | Vaysse, J., et al. 2012. J Pharm Biomed Anal. 59: 58-66. PMID: 22030075
- Analysis of herbal dietary supplements for sexual performance enhancement: first characterization of propoxyphenyl-thiohydroxyhomosildenafil and identification of sildenafil, thiosildenafil, phentolamine and tetrahydropalmatine as adulterants. | Balayssac, S., et al. 2012. J Pharm Biomed Anal. 63: 135-50. PMID: 22365331
- Simultaneous identification of hydroxythiohomosildenafil, aminotadalafil, thiosildenafil, dimethylsildenafil, and thiodimethylsildenafil in dietary supplements using high-performance liquid chromatography-mass spectrometry. | Tagami, T., et al. 2013. Shokuhin Eiseigaku Zasshi. 54: 232-6. PMID: 23863369
- Solid-phase extraction assisted dispersive liquid-liquid microextraction based on solidification of floating organic droplet to determine sildenafil and its analogues in dietary supplements. | Li, J., et al. 2017. J Sep Sci. 40: 3120-3129. PMID: 28618213
- Safety and Quality Concerns Regarding Over-the-Counter Sexual Enhancement Products Sold in the USA Market Pose a Major Health Risk. | Ahmed, M., et al. 2016. J Addict Res Ther. 7: PMID: 29214098
- Novel synthesized attapulgite nanoparticles-based hydrophobic monolithic column for in-tube solid-phase microextraction of thiosildenafil, pseudovardenafil, and norneosildenafil in functional foods. | Dong, L., et al. 2021. Anal Bioanal Chem. 413: 1871-1882. PMID: 33469710
Inhibitor of:
PDE5A.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Thiosildenafil, 10 mg | sc-208435 | 10 mg | $320.00 |