Anti-Sprouty 1 Antibody H-2 è un monoclonale di topo IgG1 κ Sprouty 1 antibody, citato in 2 pubblicazioni, fornito in 200 µg/ml
raised against amino acids 61-180 mapping within an internal region of Sprouty 1 of human origin
Sprouty 1 Antibody (H-2) é raccomandato per il rilevamento di Sprouty 1 di origine human in WB, IP, IF, IHC(P) e ELISA
Sprouty 1 Antibody (H-2) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Contattaci per ricevere un FREE 10 µg sample di Sprouty 1 (H-2): sc-365520.
m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) and m-IgG1 BP-HRP (mouse IgG1 binding protein-HRP) are the preferred secondary detection reagents for Sprouty 1 Antibody (H-2) for WB and IHC(P) applications. These reagents are now offered in bundles with Sprouty 1 Antibody (H-2) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Sprouty 1 Antibody (H-2) is a high quality monoclonal Sprouty 1 antibody (also designated SPRY1 antibody or Spry-1 antibody) suitable for the detection of the Sprouty 1 protein of human origin. Sprouty 1 Antibody (H-2) is available as both the non-conjugated anti-Sprouty 1 antibody form, as well as multiple conjugated forms of anti-Sprouty 1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Members of the Sprouty family (Sprouty 1-4) are inducible negative regulators of growth factors that act through tyrosine kinase receptors. Mammalian Sprouty homologs share a well-conserved cysteine-rich C-terminal domain with their Drosophila counterparts. Both Sprouty 1 and 2 are anchored to membranes by palmitoylation, associate with caveolin-1 in perinuclear and vesicular structures and are phosphorylated on Serine residues. Upon stimulation, a subset is recruited to the leading edge of the plasma membrane. Sprouty 2 can associate with c-Cbl, a down regulator of RTK signaling, and inhibits the activities of several growth factors. Sprouty 2 also functions as a negative regulator of embryonic lung morphogenesis and growth. The well-conserved C-terminus of Sprouty contains two domains which are necessary for Sprouty 2 co-localization with microtubules and translocation to membrane ruffles. In addition, the C-terminus is required for the inhibition of cell migration and proliferation. In conclusion, members of Sprouty inhibit FGF and VEGF-mediated cell proliferation, suggesting that they may regulate angiogenesis in normal and disease processes.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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