Septin 5 Antibody (SP19): sc-65511

Septin 5 Antibody (SP19) is a mouse monoclonal IgG1 antibody that detects Septin 5 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Septin 5 plays a crucial role in the organization of the cytoskeleton and is involved in various cellular processes, including cytokinesis and the regulation of exocytosis. Septin 5′s ability to form heteropolymer complexes with other septins is essential for maintaining cellular architecture and function. Notably, Septin 5 is localized to the cytoplasm and is particularly abundant in the adult neocortex, where Septin 5 contributes to the structural integrity of neuronal cells. Septin 5′s interaction with other cytoskeletal components is vital for proper cell division and signaling pathways, making Septin 5 a significant focus of research in neurobiology and cancer studies. Additionally, Septin 5 has been implicated in the formation of neurofibrillary tangles, which are associated with neurodegenerative diseases, highlighting Septin 5′s importance in both normal physiology and disease states. With diverse roles and critical functions, anti-Septin 5 antibody (SP19) is an invaluable tool for researchers investigating the complexities of cellular dynamics and pathology.

The preferred Septin 5 antibody is Septin 5 Antibody (SP18): sc-20040.