SD 1008 CAS: 960201-81-4
MF: C18H19NO5
MW: 329.35
An apoptosis inducer & JAK2/STAT3 signaling pathway inhibitor.

SD 1008 (CAS 960201-81-4)

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Nomi alternativi: (1R,5R,6R,7S)-rel-4-Oxo-8-(phenylmethyl)-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid 6,7-dimethyl ester
Applicazione: SD 1008 is a apoptosis inducer & JAK2/STAT3 signaling pathway inhibitor
Numero CAS: 960201-81-4
Peso molecolare: 329.35
Formula molecolare: C18H19NO5
Solo per uso in Ricerca. Non previsto per Uso Diagnostico o Terapeutico.
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SD 1008 is reported to be a JAK2/STAT3 signaling pathway inhibitor which additionally inhibits Src. SD 1008 is noted to induce apoptosis in cell lines that express constitutively active tyrosine-phosphorylated STAT3.


Referenze

1. Duan, Z., et al. 2007. Mol. Pharmacol. 72: 1137-1145. PMID: 17675586

Stato fisico :
Solid
Solubilità :
Soluble in ethanol (100 mM), and DMSO (5 mM).
CONSERVAZIONE :
Store at room temperature
Solo per uso in Ricerca. Non previsto per Uso Diagnostico o Terapeutico.
Numero MDL :
MFCD18086855

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