Date published: 2026-4-24

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S-Metolachlor (CAS 87392-12-9)

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Alternate Names:
2-Chloro-N-(2-ethyl-6-methylphenyl)-N-[(1S)-2-methoxy-1-methylethyl]acetamide
Application:
S-Metolachlor is The S isoform of the aniline derivative herbicide
CAS Number:
87392-12-9
Molecular Weight:
283.79
Molecular Formula:
C15H22ClNO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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S-Metolachlor is a selective herbicide that functions by inhibiting the growth of weeds in experimental applications. It acts by preventing the synthesis of fatty acids in target plants, disrupting their cellular membranes and leading to their eventual death. S-Metolachlor′s mechanism of action involves targeting the enzyme acetolactate synthase. By interfering with this key enzyme, S-Metolachlor disrupts the normal metabolic processes of the target plants, ultimately leading to their inability to survive and grow. This herbicide′s mechanism of action at the molecular level involves binding to the active site of acetolactate synthase, thereby blocking its function and causing metabolic dysfunction in the target plants.


S-Metolachlor (CAS 87392-12-9) References

  1. Effect of chiral differences of metolachlor and its (S)-isomer on their toxicity to earthworms.  |  Xu, D., et al. 2010. Ecotoxicol Environ Saf. 73: 1925-31. PMID: 20723980
  2. Enantioselective Oxidative Stress Induced by S- and Rac-metolachlor in Wheat (Triticum aestivum L.) Seedlings.  |  Qu, Q., et al. 2019. Bull Environ Contam Toxicol. 102: 439-445. PMID: 30734056
  3. Effects of s-metolachlor on early life stages of marbled crayfish.  |  Velisek, J., et al. 2019. Pestic Biochem Physiol. 153: 87-94. PMID: 30744900
  4. Metabolic resistance to S-metolachlor in two waterhemp (Amaranthus tuberculatus) populations from Illinois, USA.  |  Strom, SA., et al. 2020. Pest Manag Sci. 76: 3139-3148. PMID: 32309896
  5. The agrochemical S-metolachlor disrupts molecular mediators and morphology of the swim bladder: Implications for locomotor activity in zebrafish (Danio rerio).  |  Yang, L., et al. 2021. Ecotoxicol Environ Saf. 208: 111641. PMID: 33396161
  6. The role of two organic amendments to modify the environmental fate of S-metolachlor in agricultural soils.  |  Marín-Benito, JM., et al. 2021. Environ Res. 195: 110871. PMID: 33581091
  7. Mechanism of Resistance to S-metolachlor in Palmer amaranth.  |  Rangani, G., et al. 2021. Front Plant Sci. 12: 652581. PMID: 33777086
  8. Effects of S-metolachlor on wheat (Triticum aestivum L.) seedling root exudates and the rhizosphere microbiome.  |  Qu, Q., et al. 2021. J Hazard Mater. 411: 125137. PMID: 33858101
  9. Metabolic Pathways for S-Metolachlor Detoxification Differ Between Tolerant Corn and Multiple-Resistant Waterhemp.  |  Strom, SA., et al. 2021. Plant Cell Physiol. 62: 1770-1785. PMID: 34453831
  10. Bioaccumulation, metabolism and endocrine-reproductive effects of metolachlor and its S-enantiomer in adult zebrafish (Danio rerio).  |  Ou-Yang, K., et al. 2022. Sci Total Environ. 802: 149826. PMID: 34455281
  11. Leaching and degradation of S-Metolachlor in undisturbed soil cores amended with organic wastes.  |  Dollinger, J., et al. 2022. Environ Sci Pollut Res Int. 29: 20098-20111. PMID: 34725758
  12. Spray drift potential of dicamba plus S-metolachlor formulations.  |  Canella Vieira, B., et al. 2022. Pest Manag Sci. 78: 1538-1546. PMID: 34964546
  13. Combined effects of S-metolachlor and benoxacor on embryo development in zebrafish (Danio rerio).  |  Liu, S., et al. 2022. Ecotoxicol Environ Saf. 238: 113565. PMID: 35512469

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

S-Metolachlor, 100 mg

sc-236696
100 mg
$47.00