Anti-RNF8 Antibody B-2 è un monoclonale di topo IgG1 κ RNF8 antibody, citato in 48 pubblicazioni, fornito in 200 µg/ml
generato contro gli amminoacidi 186-485 mappati al C-terminus di RNF8 di origine human
RNF8 Antibody (B-2) é raccomandato per il rilevamento di RNF8 di origine mouse, rat e human in WB, IP, IF, IHC(P) e ELISA
RNF8 Antibody (B-2) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Contattaci per ricevere un FREE 10 µg sample di RNF8 (B-2): sc-271462.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for RNF8 Antibody (B-2) for WB and IHC(P) applications. These reagents are now offered in bundles with RNF8 Antibody (B-2) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
RNF8 Antibody (B-2) is a high quality monoclonal RNF8 antibody (also designated Ring Finger Protein 8 antibody, UBC13/UEV-Interacting Ring Finger Protein antibody, C3HC4-Type Zinc Finger Protei antibody, HRNF8 or Ring Finger Protein 8, E3 Ubiquitin Protein Ligase antibody) suitable for the detection of the RNF8 protein of mouse, rat and human origin. RNF8 Antibody (B-2) is available as both the non-conjugated anti-RNF8 antibody form, as well as multiple conjugated forms of anti-RNF8 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The RING finger motif is a specialized DNA-binding zinc finger domain found in many transcriptional regulatory proteins. The ring finger protein (RNF) family includes any protein containing the signature RING finger motif. RNF8 is a ubiquitously expressed nuclear RING finger protein that acts as an E3 ubiquitin-protein ligase. It is required for the ubiquitination of some nuclear proteins and promotes their subsequent degradation. The heterodimeric ubiquitin-conjugating enzyme UBC13 interacts with RNF8, and they co-localize in the nucleus. RNF8 may regulate mediation of UBC13 polyubiquitylation by elongating the ubiquitin chains. RNF8 also binds to Retinoid X receptor alpha (RXRα), a member of the steroid hormone receptor superfamily. It increases RXRα-mediated transactivation of the RXRα-responsive element (RXRE) promoter in a dose-dependent manner, suggesting that RNF8 is a regulator of RXRα-mediated transcriptional activity.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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