Quinaprilat-d5 CAS: 1279034-23-9
MF: C23H21D5N2O5
MW: 415.49
A deuterium-labeled metabolite of quinapril.

Quinaprilat-d5 (CAS 1279034-23-9)

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Nomi alternativi: (3S)-2-[(2S)-2-[[(1S)-1-Carboxy-(3-phenyl-d5)propyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid; Accuprin-d5; CI-928-d5
Applicazione: Quinaprilat-d5 is a deuterium-labeled metabolite of quinapril
Numero CAS: 1279034-23-9
Peso molecolare: 415.49
Formula molecolare: C23H21D5N2O5
Solo per uso in Ricerca. Non previsto per Uso Diagnostico o Terapeutico.
* Vedere Certificato di Analisi per informazioni sul lotto specifico (incluso il contenuto d'acqua).
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Quinaprilat-d5 is a deuterium-labeled metabolite of Quinapril and an angiotensin converting enzyme (ACE) inhibitor. This compound prevents the conversion of angiotensin I to angiotensin II, which is a potent vasoconstrictor. This labeled compound is useful in kinetic isotope effect studies as well as for use as an internal standard in NMR experiments.


Referenze

Maurer, H., et al.: Ther. Drug. Monit., 20, 706 (1998) Yamada, S., et al.: Biol. Pharm. Bull., 26, 872 (2003)

Stato fisico :
Solid
Solubilità :
Soluble in Methanol
CONSERVAZIONE :
Store at -20° C
Punto di scioglimento :
166-168° C (lit.)
Solo per uso in Ricerca. Non previsto per Uso Diagnostico o Terapeutico.
PubChem CID :
SMILES :
[2H]C1=C([2H])C([2H])=C(CC[[email protected]](N[[email protected]@H](C)C(=O)N2CC3=C(C[[email protected]]2C(O)=O)C=CC=C3)C(O)=O)C([2H])=C1[2H]

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