Date published: 2026-4-24

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Propofol Glucuronide-d17 (CAS 114991-26-3 (unlabeled))

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Alternate Names:
Propofol-d17 β-D-Glucuronide
Application:
Propofol Glucuronide-d17 is a labeled version of metabolite of propofol
CAS Number:
114991-26-3 (unlabeled)
Molecular Weight:
371.50
Molecular Formula:
C18H9D17O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Propofol Glucuronide-d17 is a deuterated analog of propofol glucuronide, used as an internal standard in analytical studies to ensure accuracy and precision during quantification processes. This compound plays a pivotal role in the field of analytical chemistry, particularly in the development and validation of robust, sensitive methods for the detection and quantification of metabolites in various biological matrices. The incorporation of the deuterium atoms into the propofol glucuronide molecule increases the molecular stability and reduces exchange reactions, which are critical for achieving high-resolution mass spectrometry data. Consequently, Propofol Glucuronide-d17 is instrumental in metabolomic research and forensic applications, aiding in the study of metabolic pathways and the environmental fate of substances. Its use facilitates a deeper understanding of the metabolite profiles and enhances the reliability of analytical results, thereby supporting the advancement of scientific knowledge in bioanalytical fields.


Propofol Glucuronide-d17 (CAS 114991-26-3 (unlabeled)) References

  1. Propofol metabolites in man following propofol induction and maintenance.  |  Favetta, P., et al. 2002. Br J Anaesth. 88: 653-8. PMID: 12067002
  2. Biosynthesis of drug glucuronides for use as authentic standards.  |  Soars, MG., et al. 2002. J Pharmacol Toxicol Methods. 47: 161-8. PMID: 12628307
  3. Effects of coexpression of UGT1A9 on enzymatic activities of human UGT1A isoforms.  |  Fujiwara, R., et al. 2007. Drug Metab Dispos. 35: 747-57. PMID: 17293379
  4. Verification of propofol sulfate as a further human propofol metabolite using LC-ESI-QQQ-MS and LC-ESI-QTOF-MS analysis.  |  Maas, A., et al. 2017. Drug Metab Pers Ther. 32: 67-72. PMID: 28259866
  5. Simultaneous extraction of propofol and propofol glucuronide from hair followed by validated LC-MS/MS analyses.  |  Maas, A., et al. 2017. J Pharm Biomed Anal. 146: 236-243. PMID: 28888172

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Propofol Glucuronide-d17, 0.5 mg

sc-219659
0.5 mg
$618.00

Propofol Glucuronide-d17, 5 mg

sc-219659A
5 mg
$4494.00