PP2C alpha Antibody 7F12 è un monoclonale di topo IgG1 κ PP2Cα antibody, citato in 2 pubblicazioni, fornito in 200 µg/ml
generato contro gli amminoacidi 202-382 di di origine human
PP2C alpha Antibody (7F12) é raccomandato per il rilevamento di PP2Cα di origine mouse, rat e human in WB, IP, FCM e ELISA
PP2C alpha Antibody (7F12) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Contattaci per ricevere un FREE 10 µg sample di PP2Cα (7F12): sc-517264.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PP2Cα Antibody (7F12) for WB applications. These reagents are now offered in bundles with PP2Cα Antibody (7F12) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
PP2Cα Antibody (7F12) is a high quality monoclonal PP2C alpha antibody (also designated PP2Cα antibody) suitable for the detection of the PP2C alpha protein of mouse, rat and human origin. PP2Cα Antibody (7F12) is available as both the non-conjugated anti-PP2C alpha antibody form, as well as multiple conjugated forms of anti-PP2C alpha antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/ threonine protein phosphatases. Protein phosphatase 2Ca (PP2Ca) has broad specificity. It dephosphorylates and negatively regulates the activities of MAP kinases and MAP kinase-kinases while also inhibiting the activation of p38 and JNK kinase cascades, induced by environmental stresses. PP2Ca also induces the expression of endogenous p53 and the p53-responsive gene p21, leading to cell cycle arrest and apoptosis. The PP2Ca protein, which contains an active site containing a dinuclear metal ion center, shows highest expression in epithelial cells, as well as in the digestive tract, lung, kidney, breast, prostate, endocrine glands and brain.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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