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Poly(2-hydroxyethyl methacrylate) (CAS 25249-16-5)

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Alternate Names:
Poly(2-hydroxyethyl methacrylate) is also known as pHEMA.
Application:
Poly(2-hydroxyethyl methacrylate) is a polymer that inhibits cell adhesion to growth surfaces in culture vessels.
CAS Number:
25249-16-5
Molecular Weight:
~300,000
Molecular Formula:
(C6H10O3)n
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Poly(2-hydroxyethyl methacrylate) is a hydrophilic polymer that has been extensively investigated in materials science research. Its main utility lies in the creation of hydrogels, which can absorb significant amounts of water while maintaining structural integrity. Research involving PHEMA often focuses on its biocompatibility and permeability properties, which make it suitable for studies related to biomedical device development. In addition, PHEMA′s capacity for controlled swelling is of interest in the field of controlled release systems, where it is used to study the release kinetics of encapsulated substances. The polymer is also utilized in the examination of surface modification techniques to improve the interface between synthetic materials and biological tissues. Studies on PHEMA contribute to the understanding of polymer networks and their potential applications in creating advanced materials that mimic the properties of natural tissues.


Poly(2-hydroxyethyl methacrylate) (CAS 25249-16-5) References

  1. Evaluation of poly(2-hydroxyethyl methacrylate) gels as drug delivery systems at different pH values.  |  Ferreira, L., et al. 2000. Int J Pharm. 194: 169-80. PMID: 10692641
  2. Calcification of poly(2-hydroxyethyl methacrylate) hydrogel sponges implanted in the rabbit cornea: a 3-month study.  |  Vijayasekaran, S., et al. 2000. J Biomater Sci Polym Ed. 11: 599-615. PMID: 10981676
  3. Poly(2-hydroxyethyl methacrylate) film as a drug delivery system for pilocarpine.  |  Hsiue, GH., et al. 2001. Biomaterials. 22: 1763-9. PMID: 11396879
  4. Evaluation of porous networks of poly(2-hydroxyethyl methacrylate) as interfacial drug delivery devices.  |  Dziubla, TD., et al. 2001. Biomaterials. 22: 2893-9. PMID: 11561895
  5. Effects of negatively charged groups (carboxymethyl) on the calcification of poly(2-hydroxyethyl methacrylate).  |  Filmon, R., et al. 2002. Biomaterials. 23: 3053-9. PMID: 12069348
  6. Fiber templating of poly(2-hydroxyethyl methacrylate) for neural tissue engineering.  |  Flynn, L., et al. 2003. Biomaterials. 24: 4265-72. PMID: 12853258
  7. Poly(2-hydroxyethyl methacrylate) wound dressing containing ciprofloxacin and its drug release studies.  |  Tsou, TL., et al. 2005. J Mater Sci Mater Med. 16: 95-100. PMID: 15744596
  8. Pentablock copolymers of poly(ethylene glycol), poly((2-dimethyl amino)ethyl methacrylate) and poly(2-hydroxyethyl methacrylate) from consecutive atom transfer radical polymerizations for non-viral gene delivery.  |  Xu, FJ., et al. 2008. Biomaterials. 29: 3023-33. PMID: 18423581
  9. Directional migration of vascular smooth muscle cells guided by a molecule weight gradient of poly(2-hydroxyethyl methacrylate) brushes.  |  Ren, T., et al. 2013. Langmuir. 29: 6386-95. PMID: 23634666
  10. Hydrogen-bonds structure in poly(2-hydroxyethyl methacrylate) studied by temperature-dependent infrared spectroscopy.  |  Morita, S. 2014. Front Chem. 2: 10. PMID: 24790979
  11. Non-biofouling property of well-defined concentrated polymer brushes.  |  Yoshikawa, C., et al. 2015. Colloids Surf B Biointerfaces. 127: 213-20. PMID: 25679494
  12. A transparent wound dressing based on bacterial cellulose whisker and poly(2-hydroxyethyl methacrylate).  |  Di, Z., et al. 2017. Int J Biol Macromol. 105: 638-644. PMID: 28716748
  13. Immobilization of glucose oxidase in poly(2-hydroxyethyl methacrylate) membranes.  |  Arica, Y. and Hasirci, VN. 1987. Biomaterials. 8: 489-95. PMID: 3427149

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Poly(2-hydroxyethyl methacrylate), 10 g

sc-253284
10 g
$179.00