Pertussis Toxin (islet-activating protein) CAS: 70323-44-3
A toxin that blocks reduction of adenylate cyclase activity.

Pertussis Toxin (islet-activating protein) (CAS 70323-44-3)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 129ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
5
1
4
0
3
0
2
0
1
0
Sinonimo: PTX;Holotoxin
Applicazione: A toxin that blocks reduction of adenylate cyclase activity
Numero CAS: 70323-44-3
Purezza: >99%
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Vedere Certificato di Analisi per informazioni sul lotto specifico (incluso il contenuto d'acqua).
Invia una review per questo prodotto e ricevi 15 Cruz Credits

Pertussis Toxin (islet-activating protein), a toxin originally isolated from Bordetella pertussis, has been shown to catalyze ADP-ribosylation of a protein in membrane preparation from rat C6 glioma cells. In addition, exposure of Chinese hamster ovary cells in culture to this compound has resulted in a clustered growth pattern response. Other experiments have shown Pertussis Toxin to block the ability of inhibitory hormones to reduce adenylate cyclase activity and enhance the ability of stimulatory hormones to activate the enzyme. Mechanistic studies have shown this toxin to consist of subunit A (active) promoter, which disrupts transmembrane signaling by ADP-ribosylating eukaryotic G-proteins, and B (binding) oligomer which helps the toxin bind to cells in vivo.


Referenze

1. Tamura, M., et al. 1982. Biochemistry. 21: 5516-5522. PMID: 6293544
2. Hewlett, E.L., et al. 1983. Infect. Immun. 40: 1198-1203. PMID: 6682833
3. Bokoch, G.M., et al. 1983. J. Biol. Chem. 258: 2072-2075. PMID: 6296122
4. Kaslow, H.R., et al. 1987. Biochemistry. 26: 123-127. PMID: 3030399
5. Kaslow, H.R. and Burns, D.L. 1992. FASEB J. 6: 2684-2690. PMID: 1612292

Stato fisico :
Solid
Derivato da :
Bordetella pertussis
Solubilità :
Soluble in water (Miscible).
CONSERVAZIONE :
Store at 4° C
Solo per uso in Ricerca. Non previsto per Uso Diagnostico o Terapeutico.
WGK Germania :
3
RTECS :
XW5883750
Numero MDL :
MFCD00131841

Download SDS (MSDS)

CERTIFICATO DI ANALISI

Adobe Acrobat Reader necessario per una visualizzazione affidabile,
stampa e commenta sui documenti PDF

Pertussis Toxin (islet-activating protein)  Citazioni prodotti

Vedi quanti altri hanno usato Pertussis Toxin (islet-activating protein). Clicca sulla voce per laccesso a PubMed .

Ciatazioni 1 a1 di 1 totali

PMID: # 3158374  Fujita, N. et al. 1985. Brain Res. 333: 231-236.

Ciatazioni 1 a1 di 1 totali
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 124ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 14ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

La Santa Cruz Biotechnology, Inc. è un leader mondiale nello sviluppo di prodotti per il mercato della ricerca biomedica. Chiamaci al numero gratuito 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. Tutti i diritti riservati. "Santa Cruz Biotechnology", ed il logo Santa Cruz Biotechnology, Inc."Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", il logo San Juan Ranch, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", ed "EZ Touch" sono marchi registrati dalla Santa Cruz Biotechnology, Inc.
Tutti i marchi sono proprietà dei rispettivi proprietari.