p-Atm Antibody 10H11.E12 è un monoclonale di topo IgG1 κ, citato in 93 pubblicazioni, fornito in 200 µg/ml
raised against a synthetic phosphopeptide corresponding to amino acids Ser 1981 surrounding the Ser 1981 phosphorylation site of human ATM
p-Atm Antibody (10H11.E12) é raccomandato per il rilevamento di Ser 1981 phosphorylated Atm di origine mouse, rat e human in WB, IP, IF e IHC(P)
p-Atm Antibody (10H11.E12) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Contattaci per ricevere un FREE 10 µg sample di p-Atm (10H11.E12): sc-47739.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for p-Atm Antibody (10H11.E12) for WB and IHC(P) applications. These reagents are now offered in bundles with p-Atm Antibody (10H11.E12) (see ordering information below).
Atm Inibitori per le analisi funzionali delle risposte cellulari a Atm
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3- and PI 4-kinases and the second group comprises the PIK-related kinases. The PIK-related kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy termini that is not present in the PI 3- and PI 4-kinases. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiectases) in the conjunctivae of the eyes. AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and they display delays in p53 induction. Cultured cells respond to breaks in double stranded DNA by immediate activation of ATM through autophosphorylation on serine 1981. Most human tissues, however, contain the non-phosphorylated, inactive form of Atm.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences