Monomethyl Histone H4 Antibody 5E10-D8 è un monoclonale di topo IgG1 κ, citato in 6 pubblicazioni, fornito in 200 µg/ml
raised against a short amino acid sequence containing monomethylated lysine 20 of Lys 20 monomethylated Histone H4 of human origin
Monomethyl Histone H4 Antibody (5E10-D8) é raccomandato per il rilevamento di Lys 20 monomethylated Histone H4 di origine mouse, rat e human in WB e ELISA; non cross-reattivo con Histone H4 unmethylated or dimethylated at lysine 20, nor with Histone H3
Monomethyl Histone H4 Antibody (5E10-D8) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Contattaci per ricevere un FREE 10 µg sample di Monomethyl Histone H4 (5E10-D8): sc-134221.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Monomethyl Histone H4 Antibody (5E10-D8) for WB applications. These reagents are now offered in bundles with Monomethyl Histone H4 Antibody (5E10-D8) (see ordering information below).
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Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fibers. Two molecules of each of the four core histones (H2A, H2B, H3 and H4) form the octamer, which is comprised of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Human and mouse Histone H4 are subject to methylation at Lys 20, a modification that may be necessary for select DNA transactions or chromatin state transitions.
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